Pharmaceutical Grade
Hdroxypropyl Methyl Cellulose (HPMC) is a multi-functional pharmaceutical adjuvant which can be used as thickener, dispersant, emulsifier and film-forming agent. As film coating and binder, it can improve the dissolution rate of drugs. It can also be used as a suspension aid, host material in ophthalmic preparations and etc.
Recommend Application
Binders for tablets.
Film coating materials.
Matrix materials for sustained-release tablets.
Recommend Grade
• Hypromellose Type C: High Methoxy and High Hydroxypropyl content
• Hypromellose Type D: High Methoxy and Low Hydroxypropyl content
• Hypromellose Type E: Medium Methoxy and Medium Hydroxy propyl content
Type | Letter Code | Methoxy Content % | Hydroxypropyl Content % |
1828 | C | 16.5-20.0 | 23.0-32.0 |
2208 | D | 19.0-24.0 | 4.0-12.0 |
2906 | D | 27. 0-30.0 | 4.0-7.5 |
2910 | E | 28.0-30.0 | 7.0-12.0 |
It is not uncommon for some manufacturers to use their own codes for different grades of hypromellose. For example, Dupont (formely, Dow
Chemical) uses codes E, F, and K, which principally indicate the degree of substitution.
• Hypromellose K grades correspond to Hypromellose 2208
• Hypromellose F grades correspond to Hypromellose 2906
• Hypromellose E grades correspond to Hypromellose 2910
In addition, the letter codes above may be accompanied by a number that indicates the viscosity of a 2% aqueous solution, usually multiplied by
100 as C or 1000 as M.
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Faq
Q:What are the primary application areas of HPMC in the construction industry?
A: HPMC is mainly used in tile adhesives, wall putty, cement-based mortars, gypsum-based mortars, self-leveling floors, and external wall insulation mortars.
Q:How to choose the appropriate HPMC variety?
A: When selecting HPMC, consider the specific application area and performance requirements, including viscosity, solubility, and water retention properties.
Q:What are the usage methods and precautions for HPMC?
A: The usage method mainly involves gradually adding HPMC to water while stirring until fully dissolved. Precautions include avoiding adding too much HPMC at once to prevent clumping.
Q:Can HPMC be mixed with other additives in construction materials?
A: Yes, HPMC can be mixed with various additives, such as redispersible polymer powder, cellulose ethers, and defoamers, depending on the specific application requirements.
Q:What are the storage conditions for HPMC?
A: HPMC should be stored in a dry, cool, and well-ventilated environment, avoiding direct sunlight and high temperatures.
Q:What are the precautions for HPMC transportation?
A: When transporting HPMC, ensure the packaging is intact and undamaged, avoid moisture and heat exposure, and do not mix with toxic or hazardous items.